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Malegra 50 is really awesome, but it doesn’t work so well when I have a couple of drinks. I reckon alcohol kills the effect of this drug. It provides me enough time to rock on and those few hours are good. Worth a try!
Brent Varner
 
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Erectile Dysfunciton

 

Erectile Dysfunction or ED also known as repeated penile failure in men is actually the technical term used for male impotence issue. Erectile dysfunction is a condition where man cannot achieve erection or it may not be hard enough for a satisfactory sexual intercourse when he is willing to have it even in presence of sexual arousal.

Physiology of an erection, how is erection actually caused?

Penile erection in men is managed by two mechanisms, first one is the reflex erection when penile shaft is touched and the second kind of erection is psychogenic erection, which occurs with the help of stimulation. For both the kinds of erection an intact neural system is essential to achieve and maintain penile erection. However, penile consists of two chambers that run parallel to the length of the penile. Spongy tissue in the penile fills chamber, sexual stimulation of penile shaft leads to the secretion of nitric oxide that causes relaxation of the smooth muscles and enhances flow of blood in the penile, making male sex organ expand and become harder for session of making love.

ED condition affects about 25 million adult men in the USA alone, around 80% of Erectile Dysfunction cases happen because of the physical factors. In fact erectile dysfunction takes place only because of three factors like:

Sildenafil Citrate, Tadalafil, Vardenafil and Avanafil are such components that are known and 100% effective for treating Erectile Dysfunction issue in men. Component composed in various medications with various strengths and forms are famous and most reliable ED solutions.

All the ingredients Sildenafil Citrate, Tadalafil, Vardenafil and Avanafil in medicine works by inhibiting some natural chemicals called PDE-5 or phosphodiesterase type 5 that serves to make the male sex organ turn flaccid. Thus ED solution belongs to the class of PDE-5 inhibitor drugs. PDE-5 component tend to degrade cGMP enzyme or cyclic guanomonosine phosphate, which is known for relaxing penile muscles to allow appropriate blood flow for a perfect erection. Thus by inhibiting PDE-5 enzymes Erectile Dysfunction medicine pill restricts degradation of cyclic guano monosine phosphate and thus aids in achieving erection that is harder enough for intercourse and lasts for longer time.

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